EMPIAR-PDBj - Electron Microscopy Public Image Archive

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Release date	Imageset	Title	Authors and references	Size	Resolution
2026-03-23	EMPIAR-12980	Single particle cryo-EM dataset of influenza hemagglutinin (A/Hong Kong/1/1968, H3N2) following ultrasonic excitation [7000 multi-frame micrographs composed of 50 frames each in TIFF format]	Williams HM, Curtis WA, Haubner M, Hruby J, Drabbels M, Lorenz UJ [Pubmed: 41000704] [DOI: 10.1101/2025.09.14.676144] EMD-54831	4.1 TB	2.7 Å
2026-03-23	EMPIAR-12982	Single particle cryo-EM dataset of human C-reactive protein following ultrasonic excitation [10602 multi-frame micrographs composed of 50 frames each in TIFF format]	Williams HM, Curtis WA, Haubner M, Hruby J, Drabbels M, Lorenz UJ [Pubmed: 41000704] [DOI: 10.1101/2025.09.14.676144] EMD-54833 EMD-54835	6.4 TB	3.2 - 3.7 Å
2026-03-23	EMPIAR-12983	Single particle cryo-EM dataset of human C-reactive protein jetted control sample [12000 multi-frame micrographs composed of 50 frames each in TIFF format]	Williams HM, Curtis WA, Haubner M, Hruby J, Drabbels M, Lorenz UJ [Pubmed: 41000704] [DOI: 10.1101/2025.09.14.676144] EMD-54834 EMD-54836	6.8 TB	3.3 - 4.3 Å
2026-03-23	EMPIAR-13127	Single particle cryo-EM dataset of the light-driven sodium pump ErNaR in the O2 state prepared by jet vitrification [28574 multi-frame micrographs composed of 50 frames each in EER format]	Haubner M, Williams HM, Hruby J, Straub MS, Guskov A, Kovalev K, Drabbels M, Lorenz UJ [Pubmed: 41332690] [DOI: 10.1101/2025.11.21.689681] EMD-55769 9tbf	7.2 TB	3.3 Å
2026-03-23	EMPIAR-13296	Ribosomal RNA modifications around the peptidyl transfer center stimulate catalytic activity and prevent the formation of alternative structures [multiple data sets in MRC and TIFF formats]	Larsson DSD, Selmer M [DOI: 10.64898/2026.03.01.708810] EMD-55349 EMD-55427 EMD-55428 EMD-55429 EMD-55430 EMD-55432 EMD-55433 EMD-55434 EMD-55435 EMD-55436 EMD-55437 EMD-55415 EMD-55467 EMD-55468 EMD-55469 EMD-55470 EMD-55471 EMD-55472 EMD-55473 EMD-55474 EMD-55475 EMD-55476 EMD-55618 EMD-55702 EMD-55703 EMD-55704 EMD-55705 EMD-55706 EMD-55707 EMD-55708 EMD-55709 EMD-55710 EMD-55711 9syh 9t19 9t1a 9t1b 9t1c 9t1e 9t1f 9t1g 9t1h 9t1i 9t1j 9t0y 9t2j 9t2k 9t2l 9t2m 9t2n 9t2o 9t2p 9t2q 9t2r 9t2s 9t6m 9t8k 9t8l 9t8m 9t8n 9t8o 9t8p 9t8q 9t8r 9t8s 9t8t	7.7 TB	1.87 - 3.07 Å
2026-03-23	EMPIAR-13298	Cryo electron tomography of yeast FIB-milled lamella after sublimation [657 multi-frame micrographs composed of 6 frames each in MRC format]	Bondy AL, Valentin Gese G, Thersleff T, Hallberg BM	857.7 GB	—
2026-03-23	EMPIAR-13315	Single Particle cryo-EM dataset of Fab fragment, Fab20, bound to recombinant human CD40 ligand [3360 multi-frame micrographs composed of 56 frames each in TIFF format]	Kristoffersen EL, Schinkel T [Pubmed: 41742604] [DOI: 10.1002/eji.70158] EMD-52634 9i5n	2.0 TB	3.4 Å
2026-03-23	EMPIAR-13332	Cryo-EM structures of alpha5beta1 integrin in complex with NeoNectin candidate 2, open and closed conformation [multiple data sets in TIFF and MRC formats]	Werther R [Pubmed: 40489013] [DOI: 10.1002/adma.202500872] EMD-46902 EMD-47968 9dia 9ef2	1.1 TB	2.97 - 3.36 Å
2026-03-22	EMPIAR-13124	Single particle cryo-EM dataset of mouse heavy chain apoferritin prepared by jet vitrification [6560 multi-frame micrographs composed of 50 frames each in EER format]	Haubner M, Williams HM, Hruby J, Straub MS, Guskov A, Kovalev K, Drabbels M, Lorenz UJ [Pubmed: 41332690] [DOI: 10.1101/2025.11.21.689681] EMD-55761	653.8 GB	1.25 Å
2026-03-20	EMPIAR-12167	Dissecting human monoclonal antibody responses from mRNA- and protein-based booster vaccinations against XBB.1.5 SARS-CoV-2 [6112 micrographs in MRC format]	Bajic GB, Jaiswal DJ [Pubmed: 40456237] [DOI: 10.1016/j.lanmic.2025.101103] EMD-45443 9cci	536.7 GB	2.65 Å
2026-03-20	EMPIAR-12414	CryoEM structure of a broadly neutralizing anti-SARS-CoV-2 mAb 52 [6614 micrographs in MRC format]	Jaiswal DJ, Bajic GB [Pubmed: 41071904] [DOI: 10.1126/sciimmunol.adu4107] EMD-47426 9e21	600.1 GB	3.1 Å
2026-03-20	EMPIAR-13115	Single particle cryo-EM dataset of as-prepared Bos taurus mitochondrial complex I in MSP2N2 nanodiscs treated with NADH [13056 multi-frame micrographs composed of 40 frames each in TIFF format]	Chung I, Hirst J [Pubmed: 41786699] [DOI: 10.1038/s41467-026-70030-0] EMD-55030 EMD-55031 EMD-55032 EMD-55033 EMD-55034 9smf 9smg 9smh 9smi	5.2 TB	2.01 - 2.61 Å
2026-03-20	EMPIAR-13132	Single particle cryo-EM dataset of as-prepared Bos taurus mitochondrial complex I (oxidised) in MSP2N2 [6780 multi-frame micrographs composed of 40 frames each in TIFF format]	Chung I, Hirst J [Pubmed: 35589726] [DOI: 10.1038/s41467-022-30506-1] EMD-14132 EMD-14133 EMD-14134 EMD-14139 EMD-14140 7qsk 7qsl 7qsm 7qsn 7qso	3.0 TB	2.3 - 3.02 Å
2026-03-20	EMPIAR-13379	Clostridium butyricum Argonaute catalytic mutant in ternary form (bound to guide DNA and target DNA) [14596 multi-frame micrographs composed of 50 frames each in EER format]	Barendse P, van Drimmelen M, Pacesa M, Sivaraman A, Zhang DK, Nickel L, Niault T, Lindhoud S, Roosjen M, Hegge JW, Park K, Correia BE, van der Oost J, Joo C, Westphal AH, Swarts DC	4.7 TB	—
2026-03-19	EMPIAR-12151	Dissecting human monoclonal antibody responses from mRNA and protein-based booster vaccinations against XBB1.5 SARS-CoV-2 [6034 micrographs in MRC format]	Bajic GB, Civljak AC [Pubmed: 40456237] [DOI: 10.1016/j.lanmic.2025.101103] EMD-45444 9ccj	529.8 GB	2.37 Å
2026-03-19	EMPIAR-12412	Reducing the effects of radiation damage in cryo-EM using liquid helium cooling [2946 multi-frame micrographs composed of 120 frames each in TIFF format]	Dickerson JL, Naydenova K, Peet MJ, Wilson H, Nandy B, McMullan G, Morrison R, Russo CJ [Pubmed: 40261934] [DOI: 10.1073/pnas.2421538122] EMD-51777 EMD-51778 EMD-51779 EMD-51780 EMD-51781 EMD-51782 EMD-51783 EMD-51784	381.8 GB	2.1 - 3.32 Å
2026-03-19	EMPIAR-13148	Convergent and clonotype-specific mutations in the light chain drive affinity maturation of a public antibody targeting a cryptic epitope on S2 of sarbecoviruses [8135 multi-frame micrographs composed of 32 frames each in TIFF format]	Bajic GB [Pubmed: 40803328] [DOI: 10.1016/j.celrep.2025.116122] EMD-48507 9mpw	1.5 TB	3.37 Å
2026-03-19	EMPIAR-13378	Clostridium butyricum Argonaute wild type apo protein complexed with de novo designed binder2 [7097 multi-frame micrographs composed of 50 frames each in EER format]	Barendse P, van Drimmelen M, Pacesa M, Sivaraman A, Zhang DK, Nickel L, Niault T, Lindhoud S, Roosjen M, Hegge JW, Park K, Correia BE, van der Oost J, Joo C, Westphal AH, Swarts DC	3.1 TB	—
2026-03-18	EMPIAR-12203	Cryo-EM of Nipah virus F in complex with a bnAb [3383 micrographs in MRC format]	Bajic G EMD-45622 9cin	297.0 GB	3.03 Å
2026-03-18	EMPIAR-13371	Clostridium butyricum Argonaute catalytic mutant in ternary form (bound to guide DNA and target DNA) and de novo designed Dimbd2 [12538 multi-frame micrographs composed of 50 frames each in EER format]	Barendse P, van Drimmelen M, Pacesa M, Sivaraman A, Zhang DK, Nickel L, Niault T, Lindhoud S, Roosjen M, Hegge JW, Park K, Correia BE, van der Oost J, Joo C, Westphal AH, Swarts DC	4.0 TB	—
2026-03-17	EMPIAR-13099	Focused Ion Beam - Scanning Electron Microscopy volume of the aboral pole of a Nematostella Vectensis polyp [2347 multi-frame micrographs composed of 1 frames each in TIFF format]	Basu SH, Ronchi PR, Ikmi AI [DOI: 10.1101/2025.05.26.656114]	16.4 GB	—
2026-03-17	EMPIAR-13260	FIB-SEM of 2-cell-stage like cells (2CLC) in mouse embryonic stem cells (mESC) [multiple data sets in MRC format]	Ruiz S, Narayan K	11.8 GB	—
2026-03-17	EMPIAR-13369	Clostridium butyricum Argonaute wild type protein in apo form [7472 multi-frame micrographs composed of 60 frames each in EER format]	Barendse P, van Drimmelen M, Pacesa M, Sivaraman A, Zhang DK, Nickel L, Niault T, Lindhoud S, Roosjen M, Hegge JW, Park K, Correia BE, van der Oost J, Joo C, Westphal AH, Swarts DC	3.1 TB	—
2026-03-17	EMPIAR-13370	Clostridium butyricum Argonaute wild type protein in binary form (single stranded guide DNA bound) [18989 multi-frame micrographs composed of 60 frames each in EER format]	Barendse P, van Drimmelen M, Pacesa M, Sivaraman A, Zhang DK, Nickel L, Niault T, Lindhoud S, Roosjen M, Hegge JW, Park K, Correia BE, van der Oost J, Joo C, Westphal AH, Swarts DC	4.1 TB	—
2026-03-16	EMPIAR-12558	Ice-free ESIBD structure of GroEL [111 multi-frame micrographs composed of 1874 frames each in EER format]	Eriksson L EMD-52627	106.4 GB	6.73 Å

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Citations

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)