EMPIAR-13028 - Cryo-correlative light and electron tomography of dopaminergic axonal varicosities reveals non-synaptic modulation of cortico-striatal synapses [400 reconstructed volumes in MRC format]

EMPIAR-13028

Cryo-correlative light and electron tomography of dopaminergic axonal varicosities reveals non-synaptic modulation of cortico-striatal synapses [400 reconstructed volumes in MRC format]

Publication:

Cryo-correlative light and electron tomography of dopaminergic axonal varicosities reveals non-synaptic modulation of cortico-striatal synapses

Paul Lapios PL, Robin Anger RA, Vincent Paget-Blanc VPB, Esther Marza EM, Vladan Lucic VL, Remi Fronzes RF, Etienne Herzog EH, David Perrais DP

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Related EMDB entry:

Deposited:

2025-10-06

Released:

2025-10-15

Last modified:

2025-10-15

Imageset size:

133.04 GB

Imageset DOI:

10.6019/EMPIAR-13028

Experimental metadata:

Download xml json

Contains:

reconstructed volumes

Image Sets

1. Tomograms and 3D models of dopaminergic (DA), glutamatergic (GLU), hub synapses (DHS).

Category:

reconstructed volumes

Image format:

MRC

No. of images or tilt series:

400

Image size:

(None, None)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(15.59, 15.59)

Details:

Reconstructed tomograms are accompanied by 3D models, manually segmented with 3dmod. The color code helps to identify the dopaminergic (magenta) or glutamatergic (green) synaptosome.

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Citations

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The vault associates with membranes in situ.

Geißler K, Kreysing JP, Wang Y, Glushkova D, Obarska-Kosinska A, Hoffmann PC, Böhm S, Schmidt A, Meier-Credo J, Langer JD, Hummer G, Beck M. (2026)