Human polymerase epsilon bound to PCNA and DNA with a pre-existing mismatch in the blocked conformation [18426 multi-frame micrographs composed of 50 frames each in TIFF format]
Publication:
The proofreading mechanism of the human leading-strand DNA polymerase ε holoenzyme
The micrographs are the average, without any realigment, of 50 raw movie frames (accumulating 60 electron per squared Angstrom in a 1.0 second exposure).
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