EMPIAR-11807 - Cryo-EM structure of the CAK-CT7030 complex [10017 multi-frame micrographs composed of 909 frames each in EER format]

EMPIAR-11807

Cryo-EM structure of the CAK-CT7030 complex [10017 multi-frame micrographs composed of 909 frames each in EER format]

Publication:

High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design

Cushing VI, Koh AF, Feng J, Jurgaityte K, Bondke A, Kroll SHB, Barbazanges M, Scheiper B, Bahl AK, Barrett AGM, Ali S, Kotecha A, Greber BJ

Nature communications 15 (2024)

PMID: 38480681

DOI: 10.1038/s41467-024-46375-9

Related EMDB entry:

EMD-17754

Deposited:

2023-12-05

Released:

2024-05-20

Last modified:

2024-05-20

Imageset size:

4.07 TB

Imageset DOI:

10.6019/EMPIAR-11807

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. EER movies, CAK-CT7030, grid BG51-1

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

10017

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.57, 0.57)

Details:

EER movies. The gain reference can be found in the top directory (data/RNDK3_231024_BG51-1_D8eps/).

Files:

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Citations

High-resolution ab initio reconstruction enables cryo-EM structure determination of small particles

Kim K, Li H, Clarke OB. (2025)

CLEM-Reg: an automated point cloud-based registration algorithm for volume correlative light and electron microscopy.

Krentzel D, Elphick M, Domart MC, Peddie CJ, Laine RF, Shand C, Henriques R, Collinson LM, Jones ML. (2025)

Self-supervised learning for generalizable particle picking in cryo-EM micrographs.

Zamanos A, Koromilas P, Bouritsas G, Kastritis PL, Panagakis Y. (2025)

Laser flash melting cryo-EM samples to overcome preferred orientation.

Straub MS, Harder OF, Mowry NJ, Barrass SV, Hruby J, Drabbels M, Lorenz UJ. (2025)

In situ structure determination of conformationally flexible targets using nextPYP.

Liu HF, Zhou Y, Huang Q, Martin J, Bartesaghi A. (2025)

EMICSS: added-value annotations for EMDB entries.

Duraisamy AK, Fonseca N, Kleywegt GJ, Patwardhan A, Morris KL. (2025)

Overcoming Preferred Orientation in Cryo-EM With Ultrasonic Excitation During Vitrification

Williams HM, Curtis WA, Haubner M, Hruby J, Drabbels M, Lorenz UJ. (2025)

CryoPROS: Correcting misalignment caused by preferred orientation using AI-generated auxiliary particles.

Zhang H, Zheng D, Wu Q, Yan N, Peng H, Hu Q, Peng Y, Yan Z, Shi Z, Bao C, Hu M. (2025)

Few-shot learning for non-vitrified ice segmentation.

Vivas-Lago A, Castaño-Díez D. (2025)

Automated removal of corrupted tilts in cryo-electron tomography.

Majtner T, Turoňová B. (2025)

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