EMPIAR-12618 - Multiple steps of dynein activation by Lis1 visualized by cryo-EM [1849 multi-frame micrographs composed of 40 frames each in MRC format]

EMPIAR-12618

Multiple steps of dynein activation by Lis1 visualized by cryo-EM [1849 multi-frame micrographs composed of 40 frames each in MRC format]

Publication:

Multiple steps of dynein activation by Lis1 visualized by cryo-EM

Kendrick AA, Nguyen KHV, Ma W, Karasmanis EP, Amaro RE, Reck-Peterson SL, Leschziner AE

Nature structural & molecular biology (2025)

PMID: 40410592

DOI: 10.1038/s41594-025-01558-w

Related EMDB entry:

EMD-46919

Deposited:

2025-02-20

Released:

2025-07-03

Last modified:

2025-07-03

Imageset size:

138.94 GB

Imageset DOI:

10.6019/EMPIAR-12618

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned micrographs of yeast dynein monomer in complex with ATP

Category:

micrographs - multiframe

Image format:

MRC

No. of images or tilt series:

1849

Image size:

(None, None)

Pixel type:

16 BIT FLOAT

Pixel spacing:

(1.16, 1.16)

Details:

---

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Citations

High-resolution ab initio reconstruction enables cryo-EM structure determination of small particles

Kim K, Li H, Clarke OB. (2025)

Self-supervised learning for generalizable particle picking in cryo-EM micrographs.

Zamanos A, Koromilas P, Bouritsas G, Kastritis PL, Panagakis Y. (2025)

In situ structure determination of conformationally flexible targets using nextPYP.

Liu HF, Zhou Y, Huang Q, Martin J, Bartesaghi A. (2025)

CryoPROS: Correcting misalignment caused by preferred orientation using AI-generated auxiliary particles.

Zhang H, Zheng D, Wu Q, Yan N, Peng H, Hu Q, Peng Y, Yan Z, Shi Z, Bao C, Hu M. (2025)

Few-shot learning for non-vitrified ice segmentation.

Vivas-Lago A, Castaño-Díez D. (2025)

Automated removal of corrupted tilts in cryo-electron tomography.

Majtner T, Turoňová B. (2025)

Probabilistic single-particle cryo-EM ab initio 3D reconstruction in SIMPLE.

Van CTS, Reboul CF, Caesar JJE, Meana-Pañeda R, Lountos GT, Deme JC, Bryant OJ, Johnson S, Piczak CT, Valkov E, Lea SM, Elmlund H. (2025)

Reanalysis of cryo-EM data reveals ALK-cytokine assemblies with both 2:1 and 2:2 stoichiometries.

Felix J, De Munck S, Bazan JF, Savvides SN. (2025)

Cryo-EM Structure Reconstruction by Gaussian Splatting: Pushing the Resolution to Extreme

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2025)

Molecular exaptation by the integrin αI domain.

Hollis JA, Chan MC, Malik HS, Campbell MG. (2025)

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