EMPIAR-12088 - In situ cryoET of beta-amyloid and tau in post-mortem Alzheimer's disease brain [61 reconstructed volumes in MRC format]

EMPIAR-12088

In situ cryoET of beta-amyloid and tau in post-mortem Alzheimer's disease brain [61 reconstructed volumes in MRC format]

Publication:

CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain

Gilbert MAG, Fatima N, Jenkins J, O'Sullivan TJ, Schertel A, Halfon Y, Wilkinson M, Morrema THJ, Geibel M, Read RJ, Ranson NA, Radford SE, Hoozemans JJM, Frank RAW

Nature (2024)

PMID: 38987603

DOI: 10.1038/s41586-024-07680-x

Related EMDB entry:

EMD-50155 EMD-50159 EMD-50156 EMD-50157 EMD-50161 EMD-50153 EMD-50148 EMD-50160 EMD-50162 EMD-50152

Deposited:

2024-05-21

Released:

2024-07-16

Last modified:

2024-07-16

Imageset size:

136.31 GB

Imageset DOI:

10.6019/EMPIAR-12088

Experimental metadata:

Download xml json

Contains:

reconstructed volumes

Image Sets

1. non-demented control tomograms

Category:

reconstructed volumes

Image format:

MRC

No. of images or tilt series:

Image size:

(1024, 1024)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(9.6, 9.6)

Details:

non-demented control tomograms

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Citations

High-resolution ab initio reconstruction enables cryo-EM structure determination of small particles

Kim K, Li H, Clarke OB. (2025)

CLEM-Reg: an automated point cloud-based registration algorithm for volume correlative light and electron microscopy.

Krentzel D, Elphick M, Domart MC, Peddie CJ, Laine RF, Shand C, Henriques R, Collinson LM, Jones ML. (2025)

Self-supervised learning for generalizable particle picking in cryo-EM micrographs.

Zamanos A, Koromilas P, Bouritsas G, Kastritis PL, Panagakis Y. (2025)

Laser flash melting cryo-EM samples to overcome preferred orientation.

Straub MS, Harder OF, Mowry NJ, Barrass SV, Hruby J, Drabbels M, Lorenz UJ. (2025)

In situ structure determination of conformationally flexible targets using nextPYP.

Liu HF, Zhou Y, Huang Q, Martin J, Bartesaghi A. (2025)

CryoPROS: Correcting misalignment caused by preferred orientation using AI-generated auxiliary particles.

Zhang H, Zheng D, Wu Q, Yan N, Peng H, Hu Q, Peng Y, Yan Z, Shi Z, Bao C, Hu M. (2025)

Few-shot learning for non-vitrified ice segmentation.

Vivas-Lago A, Castaño-Díez D. (2025)

Automated removal of corrupted tilts in cryo-electron tomography.

Majtner T, Turoňová B. (2025)

Probabilistic single-particle cryo-EM ab initio 3D reconstruction in SIMPLE.

Van CTS, Reboul CF, Caesar JJE, Meana-Pañeda R, Lountos GT, Deme JC, Bryant OJ, Johnson S, Piczak CT, Valkov E, Lea SM, Elmlund H. (2025)

Reanalysis of cryo-EM data reveals ALK-cytokine assemblies with both 2:1 and 2:2 stoichiometries.

Felix J, De Munck S, Bazan JF, Savvides SN. (2025)

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