EMPIAR-11711
Cryo-EM micrographs of human DNA polymerase θ helicase domain bound to inhibitor AB25583 [4500 multi-frame micrographs composed of 2051 frames each in EER format]
Publication:

Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM

Ito F, Li Z, Minakhin L, Chandramouly G, Tyagi M, Betsch R, Krais JJ, Taberi B, Vekariya U, Calbert M, Skorski T, Johnson N, Chen XS, Pomerantz RT

Nature communications 15 (2024)

PMID: 39143110

Related EMDB entry:
Deposited:
2023-09-18
Released:
2024-08-29
Last modified:
2024-08-29
Imageset size:
5.41 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multi-frame micrographs of human DNA polymerase θ helicase domain bound to inhibitor AB25583
Category:
micrographs - multiframe
Image format:
EER
No. of images or tilt series:
4500
Image size:
(4096, 4096)
Pixel type:
BIT
Pixel spacing:
(0.92, 0.92)
Details:
We recommend dividing the total frames into 40 frame movies for motion correction. The gain reference image is in the root folder, it does not need to be flipped or rotated.
Files:
Loading...
Kim K, Li H, Clarke OB. (2025)
Zamanos A, Koromilas P, Bouritsas G, Kastritis PL, Panagakis Y. (2025)
Liu HF, Zhou Y, Huang Q, Martin J, Bartesaghi A. (2025)
Zhang H, Zheng D, Wu Q, Yan N, Peng H, Hu Q, Peng Y, Yan Z, Shi Z, Bao C, Hu M. (2025)
Vivas-Lago A, Castaño-Díez D. (2025)
Majtner T, Turoňová B. (2025)
Felix J, De Munck S, Bazan JF, Savvides SN. (2025)
Van CTS, Reboul CF, Caesar JJE, Meana-Pañeda R, Lountos GT, Deme JC, Bryant OJ, Johnson S, Piczak CT, Valkov E, Lea SM, Elmlund H. (2025)
Zeng B, Liu S, Cheng S, Xu G, Fan H. (2025)
Hollis JA, Chan MC, Malik HS, Campbell MG. (2025)