EMPIAR-11508 - CryoEM movies of extracted Arctic variant Aß42 fibrils from mouse brains labelled with methoxy-X04 [4165 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-11508

CryoEM movies of extracted Arctic variant Aß42 fibrils from mouse brains labelled with methoxy-X04 [4165 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain

Leistner C, Wilkinson M, Burgess A, Lovatt M, Goodbody S, Xu Y, Deuchars S, Radford SE, Ranson NA, Frank RAW

Nature communications 14 (2023)

PMID: 37198197

DOI: 10.1038/s41467-023-38495-5

Related EMDB entry:

EMD-16019

Deposited:

2023-04-14

Released:

2023-06-09

Last modified:

2023-06-09

Imageset size:

696.02 GB

Imageset DOI:

10.6019/EMPIAR-11508

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned Tif movie frames of Arctic abeta42 from mouse brains labelled with Methoxy-X04

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

4165

Image size:

(4096, 4096)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.94, 0.94)

Details:

---

Files:

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Citations

High-resolution ab initio reconstruction enables cryo-EM structure determination of small particles

Kim K, Li H, Clarke OB. (2025)

CLEM-Reg: an automated point cloud-based registration algorithm for volume correlative light and electron microscopy.

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CryoEMNet driven symmetry-aware molecular reconstruction through deep learning enhanced electron microscopy.

Arora S, Pan SH, Kumar S, Singh SK, Chauhan U, Alhalabi W, Arya V, Alsulami BS, Hsu CH, Chui KT, Gupta BB. (2025)

PERC: a suite of software tools for the curation of cryoEM data with application to simulation, modeling and machine learning.

Costa-Gomes B, Greer J, Juraschko N, Parkhurst J, Mirecka J, Famili M, Rangel-Smith C, Strickson O, Lowe A, Basham M, Burnley T. (2025)

Self-supervised learning for generalizable particle picking in cryo-EM micrographs.

Zamanos A, Koromilas P, Bouritsas G, Kastritis PL, Panagakis Y. (2025)

Laser flash melting cryo-EM samples to overcome preferred orientation.

Straub MS, Harder OF, Mowry NJ, Barrass SV, Hruby J, Drabbels M, Lorenz UJ. (2025)

In situ structure determination of conformationally flexible targets using nextPYP.

Liu HF, Zhou Y, Huang Q, Martin J, Bartesaghi A. (2025)

EMICSS: added-value annotations for EMDB entries.

Duraisamy AK, Fonseca N, Kleywegt GJ, Patwardhan A, Morris KL. (2025)

Global conformations of <i>Pichia pastoris</i> complex I are distinguished by the binding of a unique interdomain bridging subunit.

Lee CS, Grba DN, Wright JJ, Ivanov BS, Hirst J. (2025)

Overcoming Preferred Orientation in Cryo-EM With Ultrasonic Excitation During Vitrification

Williams HM, Curtis WA, Haubner M, Hruby J, Drabbels M, Lorenz UJ. (2025)

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